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Hiroyuki Kobayashi Selected Research

oxatomide

2/2005Identification of human P450 isoforms involved in the metabolism of the antiallergic drug, oxatomide, and its kinetic parameters and inhibition constants.
5/2004Identification of human p450 isoforms involved in the metabolism of the antiallergic drug, oxatomide, and its inhibitory effect on enzyme activity.

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Hiroyuki Kobayashi Research Topics

Disease

57Neoplasms (Cancer)
01/2022 - 02/2002
18Glioblastoma (Glioblastoma Multiforme)
04/2021 - 10/2003
16Glioma (Gliomas)
12/2021 - 10/2003
14Myocardial Infarction
04/2013 - 04/2005
12Infarction (Infarctions)
10/2013 - 11/2006
11Coronary Artery Disease (Coronary Atherosclerosis)
09/2015 - 08/2004
10Ischemia
04/2011 - 04/2005
9Infections
03/2021 - 05/2002
9Biliary Atresia
02/2009 - 07/2002
8Fibrosis (Cirrhosis)
04/2022 - 07/2002
8Brain Neoplasms (Brain Tumor)
10/2021 - 02/2012
8Leukemia
08/2018 - 01/2002
7Lymphoma (Lymphomas)
03/2021 - 08/2003
7Death (Near-Death Experience)
09/2015 - 08/2008
6Neuralgia (Stump Neuralgia)
07/2021 - 04/2007
6Pain (Aches)
01/2020 - 04/2007
6Adenocarcinoma
08/2019 - 11/2002
6Chronic Kidney Failure (Chronic Renal Failure)
12/2017 - 09/2003
6Ganglion Cysts (Ganglion)
10/2017 - 05/2003
6Inflammation (Inflammations)
09/2017 - 09/2005
6Hemorrhage
09/2015 - 12/2004
5Liver Cirrhosis (Hepatic Cirrhosis)
04/2022 - 08/2005
5Carcinoma (Carcinomatosis)
01/2022 - 07/2003
5Schizophrenia (Dementia Praecox)
03/2021 - 11/2009
5Hypoxia (Hypoxemia)
01/2020 - 05/2012
5Insulin Resistance
01/2020 - 06/2006
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2017 - 06/2009
5Cysts
01/2016 - 06/2003
5Diabetes Mellitus
09/2011 - 09/2003
5Hirschsprung Disease (Hirschsprung's Disease)
10/2007 - 12/2002
4Constipation
02/2022 - 09/2002
4Renal Cell Carcinoma (Grawitz Tumor)
01/2022 - 10/2011
4Heart Failure
06/2020 - 11/2006
4Necrosis
07/2016 - 10/2003
4Meningioma (Meningiomas)
01/2016 - 07/2013
4Pneumonia (Pneumonitis)
06/2014 - 07/2002
4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
04/2014 - 01/2004
4Hypertension (High Blood Pressure)
10/2012 - 04/2005
4Reperfusion Injury
09/2011 - 12/2007
4Respiratory Tract Infections (Respiratory Tract Infection)
01/2005 - 10/2002
4Communicable Diseases (Infectious Diseases)
06/2004 - 08/2002
3Rheumatoid Arthritis
04/2022 - 03/2013
3Neoplasm Metastasis (Metastasis)
01/2022 - 01/2010
3Cognitive Dysfunction
07/2021 - 06/2018
3Mental Disorders (Mental Disorder)
03/2021 - 10/2009
3Syncope (Fainting)
01/2021 - 01/2015
3Astrocytoma (Pilocytic Astrocytoma)
12/2020 - 10/2003
3Body Weight (Weight, Body)
06/2020 - 06/2007
3Alzheimer Disease (Alzheimer's Disease)
06/2020 - 01/2016

Drug/Important Bio-Agent (IBA)

10Temozolomide (Temodar)FDA LinkGeneric
12/2021 - 12/2006
9Pharmaceutical PreparationsIBA
03/2017 - 08/2002
8Biomarkers (Surrogate Marker)IBA
04/2022 - 04/2007
8Fatty Acids (Saturated Fatty Acids)IBA
09/2015 - 08/2004
7fluoromisonidazoleIBA
01/2020 - 02/2012
7Messenger RNA (mRNA)IBA
06/2019 - 01/2002
6CytokinesIBA
01/2022 - 05/2002
6DNA (Deoxyribonucleic Acid)IBA
01/2022 - 04/2013
6Proteins (Proteins, Gene)FDA Link
01/2021 - 02/2002
6Biological ProductsIBA
01/2020 - 11/2004
6Indicators and Reagents (Reagents)IBA
11/2017 - 01/2005
6iodofiltic acidIBA
09/2015 - 08/2004
6Nicorandil (SG 75)IBA
04/2015 - 12/2006
6Granulocyte Colony-Stimulating Factor (G-CSF)IBA
10/2013 - 04/2007
6AcetylcholinesteraseIBA
05/2007 - 09/2002
5Analgesics (Analgesic Drugs)IBA
07/2021 - 06/2019
5AcidsIBA
06/2019 - 12/2007
5Gefitinib (Iressa)FDA Link
11/2017 - 02/2014
5EnzymesIBA
07/2015 - 09/2005
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2013 - 11/2002
5Adenosine Triphosphate (ATP)IBA
10/2010 - 12/2006
5Hydroxyl RadicalIBA
07/2009 - 11/2006
4Collagen Type IV (Type IV Collagen)IBA
04/2022 - 01/2005
4LigandsIBA
07/2021 - 03/2003
4Bevacizumab (Avastin)FDA Link
04/2021 - 10/2012
4Peptides (Polypeptides)IBA
06/2020 - 01/2005
4Arginine (L-Arginine)FDA Link
01/2018 - 02/2009
4Antipsychotic Agents (Antipsychotics)IBA
01/2016 - 10/2009
4Anti-Bacterial Agents (Antibiotics)IBA
06/2007 - 10/2002
3RNA (Ribonucleic Acid)IBA
01/2022 - 01/2002
3ErbB Receptors (EGF Receptor)IBA
12/2021 - 09/2004
3Immunoglobulin G (IgG)IBA
12/2021 - 02/2002
3Methionine (L-Methionine)FDA Link
10/2021 - 04/2009
3Calcium Channels (Calcium Channel)IBA
07/2021 - 01/2020
3mirogabalinIBA
07/2021 - 01/2020
3Anti-Anxiety Agents (Anxiolytics)IBA
06/2020 - 06/2019
3Glucose (Dextrose)FDA LinkGeneric
01/2020 - 01/2015

Therapy/Procedure

35Therapeutics
12/2021 - 11/2003
19Drug Therapy (Chemotherapy)
12/2021 - 01/2004
16Renal Dialysis (Hemodialysis)
04/2019 - 09/2003
12Radiotherapy
10/2021 - 01/2008
6Oral Administration
07/2021 - 08/2009
4General Anesthesia
11/2020 - 06/2007
4Transplantation
01/2019 - 11/2004
4Anesthesia
01/2016 - 01/2010
4Laparotomy
11/2010 - 06/2003
3Chemoradiotherapy
12/2021 - 02/2013
3Colectomy
09/2021 - 10/2018
3Lasers (Laser)
03/2021 - 05/2011
3Kampo Medicine (Kampo)
08/2020 - 01/2012
3Proctectomy
06/2020 - 04/2005